Title of article :
In situ synthesis of silicon-substituted biphasic calcium phosphate and their performance in vitro Original Research Article
Author/Authors :
Chang-Weon Song، نويسنده , , Tae-Wan Kim، نويسنده , , Dong-Hyun Kim، نويسنده , , Hyeong-Ho Jin، نويسنده , , Kyu-Hong Hwang، نويسنده , , Jong Kook Lee، نويسنده , , Hong Chae Park، نويسنده , , Seog Young Yoon، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Pages :
7
From page :
39
To page :
45
Abstract :
In situ preparation of silicon (Si) substituted biphasic calcium phosphate (BCP) of hydroxyapatite (HAp)/ β-tricalcium phosphate (β-TCP) were carried out through aqueous co-precipitation method. The concentrations of added silicon were varied with the phosphor in order to obtain constant Ca/(P+Si) ratios of 1.602. X-ray diffraction (XRD) and Fourier transformed infrared (FTIR) spectroscopy were used to characterize the structure of synthesized silicon substituted BCP powders. The characterization revealed that the formation of biphasic mixtures of different HAp/ β-TCP ratios was dependent on the content of silicon. After immersing in Hanksʹ balanced salt solution (HBSS) for 1 week, 3 wt% silicon substituted BCP powders were degraded and precipitation started to be formed with small granules consisting of number of flake-like crystal onto the surface of synthesized powders. In the case of 1 wt% silicon substituted BCP powders, the degradation behavior was detected after immersion in HBSS for 3 weeks. On the other hand, silicon unsubtituted BCP powders were not degraded even after that duration. On the basis of these results, silicon substituted BCP is able to develop a new apatite phase on the surface in contact with physiological fluids faster than BCP does. This enhanced reactivity resulted in reduction for the stability of the β-TCP structure due to SiO4 tetrahedral distortion and disorder at the hydroxyl site when silicon incorporates into BCP.
Keywords :
C. X-ray diffraction , A. Ceramics , B. Chemical synthesis , D. Crystal structure
Journal title :
Journal of Physics and Chemistry of Solids
Serial Year :
2012
Journal title :
Journal of Physics and Chemistry of Solids
Record number :
1311522
Link To Document :
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