Difficult Tracheal Intubation in a Child with Cornelia De Lange Syndrome: A Case Report

Cornelia de Lange syndrome (CdLS) is a rare multiple congenital abnormalities with dominantly inherited and developmental delay. Regarding craniofacial deformities in these patients, airway management may be challenging for anesthesiologists. In these patients, pre-anesthetic evaluation must be done with exact assessment of the airway, including physical examination and radiography, CT, or MRI of the head and neck. An anesthetist should prepare the “difficult intubation set”, including a flexible fiberscope, and may need to consult with an earnose and throat (ENT) specialist if necessary for unexpected emergency situations. In this case-report, we describe a 7-year-old boy with CdLS with prominent maxilla, mouth opening restriction, and micrognathia who underwent complete repair of ventricular septal defect and pulmonary valve stenosis surgery. Anesthetic and airway management and postoperative period were uneventful.