Convenient one-pot synthesis of triphenylphosphinecarbomethoxyborane: antitumor activity and structural investigation

The reaction of equimolar quantities of trimethylaminecarbomethoxyborane and triphenylphosphine, in anhydrous 1, 2-dimethoxyethane (monoglyme), produced triphenylphosphinecarbomethoxyborane in 63% yield, via a Lewis-base exchange reaction. The structure of 1 unambiguously shows that the triphenylphosphine moiety coordinates to the boron atom with the C(O)OCH3 group intact.