Title of article :
DNA cleavage by a novel acyclic copper(II) complex
Author/Authors :
Xing-Man Xu، نويسنده , , Jun-Hua Yao، نويسنده , , Zong-Wan Mao، نويسنده , , Kai-Bei Yu، نويسنده , , Liang-Nian Ji، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A novel acyclic copper complex of Cu(L)(H2O) (H2L=N,N′-1,2-ethanediyl-bis[N-(4-methoxyphenyl)methylglycine]) has been synthesized and structurally characterized by means of X-ray single crystal diffraction. Interestingly, this Cu(II) complex has been found to cleave supercoiled DNA (pBR 322) to nicked and linear forms in aerobic condition.
Keywords :
DNA cleavage , Acyclic ligand , Acyclic complex , Copper(II) complex
Journal title :
Inorganic Chemistry Communications
Journal title :
Inorganic Chemistry Communications
