Title of article
Novel platinum complexes having chirality and free tertiary amine groups for multiple interactions with DNA
Author/Authors
Mi Sook Seo، نويسنده , , Youn Soo Sohn، نويسنده , , Beom-Seok Yang، نويسنده , , Wonwoo Nam، نويسنده , , Kwan Mook Kim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
1178
To page
1180
Abstract
Chiral ethylenediamine ligands with free tertiary amine groups and their platinum complexes are synthesized. The platinum complexes have both chirality and additional DNA interacting groups. The hydrogen bonding interactions between chlorides and two tertiary amine groups in the crystal structure lead to the dimerization of two platinum complexes having pocket-like cavity with chiral shapes.
Keywords
Platinum , Chiral amine , Multiple DNA interaction , Anticancer
Journal title
Inorganic Chemistry Communications
Serial Year
2004
Journal title
Inorganic Chemistry Communications
Record number
1316575
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