Title of article
Anaerobic photocleavage of supercoiled DNA by a ruthenium(II) substituted fluorinated porphyrin
Author/Authors
Anna McCrate، نويسنده , , Melissa Carlone، نويسنده , , Mark Nielsen، نويسنده , , Shawn Swavey، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
3
From page
537
To page
539
Abstract
Two ruthenium substituted porphyrins differing only by the substitution of a mesopentafluorophenyl group show drastically different DNA photocleavage results. The incorporation of the pentafluorophenyl group provides greater photodynamic efficiency and in addition is capable of causing DNA cleavage in the absence of oxygen.
Keywords
Photodynamic therapy , Fluorinated porphyrin , Ruthenium , DNA cleavage
Journal title
Inorganic Chemistry Communications
Serial Year
2010
Journal title
Inorganic Chemistry Communications
Record number
1318462
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