Title of article
Efficient syntheses of artificial nucleases containing mono-, di- and tri-[12]aneN3 ligating units through click chemistry
Author/Authors
Ju Zan، نويسنده , , Hao Yan، نويسنده , , Zhi-Fo Guo، نويسنده , , Zhong-Lin Lu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
3
From page
1054
To page
1056
Abstract
Mono-, di-, and tri-nucleating [12]aneN3 ligands 3–5 have been efficiently prepared through the copper-mediated click reactions between propargyl modified [12]aneN3 2 and mono-, bis-, and tri-azido compounds. Their corresponding zinc(II) and copper(II) complexes showed excellent catalytic activity and strong synergetic effects in the cleavage of RNA model phosphate diester.
Keywords
Artificial nucleases , Click chemistry , Phosphate diester , Methanolysis
Journal title
Inorganic Chemistry Communications
Serial Year
2010
Journal title
Inorganic Chemistry Communications
Record number
1318593
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