Stereoselective C-alkylation of an iron(II) dichloroclathrochelate via free-radical reactions with alcohols

Free-radical substitution of one of the two chlorine atoms of the tris-dioximate iron(II) dichloroclathrochelate with ethanol and iso-propanol radicals proceeding with high regioselectivity at their α-carbon atoms afforded the monofunctionalized macrobicyclic products, which were characterized both in solution and in solid state by multinuclear one- and two-dimensional NMR spectroscopy and X-ray crystallography, respectively.