Title of article :
Palladium-catalyzed enantioselective multiple carbonylation of 1-olefins. Synthesis of optically active 2-oxo-pentanedioates and butanedioates
Author/Authors :
Martin Sperrle، نويسنده , , Giambattista Consiglio، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
In the presence of an oxidant such as 1,4-benzoquinone, cationic palladium(II) complexes catalyze a multiple carbonylation of 1-olefins to 2-oxopentanedioates and to butanedioates. The selectivity to 2-oxopentanedioates is reasonable only for styrene as the substrate and increases by increasing the carbon monoxide pressure. The triple carbonylation is regiospecific for styrene, whereas the two possible regioisomers are formed for the aliphatic olefins. The results of regioselectivity and enantioselectivity are interpreted on the basis of common reaction intermediates for the two multiple carbonylation processes.
Keywords :
2-Oxoglutarates , Carbonylation , 1-Olefin , Carbon monoxide , Cationic palladium(II) complexes
Journal title :
INORGANICA CHIMICA ACTA
Journal title :
INORGANICA CHIMICA ACTA