• Title of article

    Effects of two representative antitumor ruthenium(III) complexes on thermal denaturation profiles of DNA

  • Author/Authors

    L. Messori، نويسنده , , A. Casini، نويسنده , , D. Vullo، نويسنده , , S.G. Haroutiunian، نويسنده , , E.B. Dalian، نويسنده , , P. Orioli، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    283
  • To page
    286
  • Abstract
    The effects of two representative antitumor ruthenium(III) complexes — namely (dichloro-1,2-propylenediamine tetraacetate ruthenium(III)) Ru(III)) RAP and (sodium trans-(dimethylsulfoxide)(imidazole)tetrachloro ruthenate(III)) NAMI — on thermal denaturation profiles of calf thymus DNA were analyzed. It is shown that both complexes slightly stabilize calf thymus DNA when tested in the concentration range 0.01
  • Keywords
    Ruthenium complexes , Antitumor activity
  • Journal title
    INORGANICA CHIMICA ACTA
  • Serial Year
    2000
  • Journal title
    INORGANICA CHIMICA ACTA
  • Record number

    1320391