Title of article :
Effects of two representative antitumor ruthenium(III) complexes on thermal denaturation profiles of DNA
Author/Authors :
L. Messori، نويسنده , , A. Casini، نويسنده , , D. Vullo، نويسنده , , S.G. Haroutiunian، نويسنده , , E.B. Dalian، نويسنده , , P. Orioli، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Pages :
4
From page :
283
To page :
286
Abstract :
The effects of two representative antitumor ruthenium(III) complexes — namely (dichloro-1,2-propylenediamine tetraacetate ruthenium(III)) Ru(III)) RAP and (sodium trans-(dimethylsulfoxide)(imidazole)tetrachloro ruthenate(III)) NAMI — on thermal denaturation profiles of calf thymus DNA were analyzed. It is shown that both complexes slightly stabilize calf thymus DNA when tested in the concentration range 0.01
Keywords :
Ruthenium complexes , Antitumor activity
Journal title :
INORGANICA CHIMICA ACTA
Serial Year :
2000
Journal title :
INORGANICA CHIMICA ACTA
Record number :
1320391
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