Author/Authors :
L. Messori، نويسنده , , A. Casini، نويسنده , , D. Vullo، نويسنده , , S.G. Haroutiunian، نويسنده , , E.B. Dalian، نويسنده , , P. Orioli، نويسنده ,
Abstract :
The effects of two representative antitumor ruthenium(III) complexes — namely (dichloro-1,2-propylenediamine tetraacetate ruthenium(III)) Ru(III)) RAP and (sodium trans-(dimethylsulfoxide)(imidazole)tetrachloro ruthenate(III)) NAMI — on thermal denaturation profiles of calf thymus DNA were analyzed. It is shown that both complexes slightly stabilize calf thymus DNA when tested in the concentration range 0.01
Keywords :
Ruthenium complexes , Antitumor activity
Journal title :
INORGANICA CHIMICA ACTA
Journal title :
INORGANICA CHIMICA ACTA