Author/Authors :
Sotiris Zartilas، نويسنده , , Sotiris K. Hadjikakou، نويسنده , , Nick Hadjiliadis، نويسنده , , Nikolaos Kourkoumelis، نويسنده , , Loukas Kyros، نويسنده , , Maciej Kubicki*، نويسنده , , Martin Baril، نويسنده , , Ian S. Butler ، نويسنده , , Spyros Karkabounas، نويسنده , , Jan Balzarini، نويسنده ,
Abstract :
Bernhard Lippert has contributed significantly to the understanding of metallamacrocyclic complexes with low valent, late transition metals. In particular, he has pioneered the preparation of metallacalixarenes such as 12-MC-3 and 16-MC-4 structure types. In this article, we provide the preparation of a new 16-MC-4, [Mn4Br4(B(tBuM)PZG)4] [Mn(HOCO2)2], complex made with the ligand potassium N,N-bis(3-methyl-5-tert-butylpyrazolylmethyl)glycinate (KB(tBuM)PZG). In addition to being the first 16-MC-4 that is composed of manganese, this complex is the first example of a transition metal [Mn(II)] being captured in the interior cavity of the 16-MC-4. We discuss how our ligand design leads to the isolated structure due to the steric bulk that has been appended to the pyrazole ligand.
Keywords :
Bioinorganic chemistry , Silver(I) complexes , Tri(p-tolyl)phosphine , crystal structures , Cytostatic activity
