Crystal structures and antimicrobial activities of copper(II) complexes of fluorine-containing thioureido ligands

Cu(II) complexes with N-4-fluorobenzoylpiperidine-1-carbothioimidate (L1−), N-2-fluorobenzoylpiperidine-1-carbothioimidate (L2−) and 2-fluorobenzoate (L3−) have been synthesized and characterized by elemental analysis, Fourier Transform infrared (FT-IR), Ultraviolet (UV) and fluorescence spectroscopy methods. The crystal structures of [Cu(L1)2], [Cu(L2)2] and [Cu2(L3)4(DMF)2] (DMF: N,N-dimethylformamide) have been determined by X-ray diffraction method. The antimicrobial activities of the complexes against the bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Shewanella sp.) and the fungi (Botrytis cinerea, Trichoderma spp., Myrothecium and Verticillium spp.) have been investigated comparing with the corresponding ligands. The experiments showed that the complexes had the stronger antibacterial and antifungal activities than the corresponding ligands had.