Author/Authors :
Olopade، نويسنده , , Olufunmilayo I and Wei، نويسنده , , Minjie، نويسنده ,
Abstract :
A new model of ovarian cancer tumor progression implicates aberrant FANCF promoter methylation that is associated with gene silencing and disruption of the Fanconi-anemia-BRCA pathway. Disruption of the pathway occurs de novo in ovarian cancers and may contribute to selective sensitivity to platinum salts.
