Title of article
A common pathway for genetic events leading to pheochromocytoma
Author/Authors
Maxwell، نويسنده , , Patrick H.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
91
To page
93
Abstract
Summary
ons in VHL, RET, NF1, SDHB, SDHC, and SDHD can give rise to pheochromocytoma/paraganglioma. These different genetic lesions may all act by decreasing the activity of a 2-oxoglutarate-dependent oxygenase, SM-20/EglN3/PHD3, resulting in reduced apoptosis of neural crest cells during development.
Journal title
Cancer Cell
Serial Year
2005
Journal title
Cancer Cell
Record number
1335665
Link To Document