Title of article
Actin and Microtubules: Working Together to Control Spindle Polarity
Author/Authors
Xu، نويسنده , , Fengfeng L. and Saunders، نويسنده , , William S.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
197
To page
199
Abstract
Centrosomes are frequently amplified in cancer cells, but centrosome clustering pathways act to minimize their detrimental impact on mitosis. Recent data published online in Genes & Developments by Kwon et al. (2008) suggest that these pathways involve microtubule motors, actin, and focal adhesions. Since centrosomal amplification is rarely seen in normal cells, could blocking clustering lead to the selective killing of tumor cells?
Journal title
Cancer Cell
Serial Year
2008
Journal title
Cancer Cell
Record number
1336862
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