• Title of article

    PAF Is in the Cabal of MLL1-Interacting Proteins that Promote Leukemia

  • Author/Authors

    Speck، نويسنده , , Nancy A. and Vakoc، نويسنده , , Christopher R.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    2
  • From page
    531
  • To page
    532
  • Abstract
    MLL1 fusions are among the most potent oncogenic drivers of leukemia development. In recent articles published in Molecular Cell and in Cancer Cell, researchers find that MLL1 fusions are reliant on a physical interaction with the PAF transcription elongation complex for their recruitment to chromatin and, consequently, leukemic transformation.
  • Journal title
    Cancer Cell
  • Serial Year
    2010
  • Journal title
    Cancer Cell
  • Record number

    1337146