Title of article
PAF Is in the Cabal of MLL1-Interacting Proteins that Promote Leukemia
Author/Authors
Speck، نويسنده , , Nancy A. and Vakoc، نويسنده , , Christopher R.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
2
From page
531
To page
532
Abstract
MLL1 fusions are among the most potent oncogenic drivers of leukemia development. In recent articles published in Molecular Cell and in Cancer Cell, researchers find that MLL1 fusions are reliant on a physical interaction with the PAF transcription elongation complex for their recruitment to chromatin and, consequently, leukemic transformation.
Journal title
Cancer Cell
Serial Year
2010
Journal title
Cancer Cell
Record number
1337146
Link To Document