Title of article
Cancer Metabolism: Is Glutamine Sweeter than Glucose?
Author/Authors
Lu، نويسنده , , Weiqin and Pelicano، نويسنده , , Helene and Huang، نويسنده , , Peng، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
2
From page
199
To page
200
Abstract
Glutamine is an essential nutrient for cancer cells. In this issue of Cancer Cell, Wang et al. (2010) show that malignant transformation by Rho GTPases leads to activation of glutaminase, which converts glutamine to glutamate to fuel cancer cell metabolism. Inhibition of glutaminase by a small compound effectively suppresses oncogenic transformation.
Journal title
Cancer Cell
Serial Year
2010
Journal title
Cancer Cell
Record number
1337224
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