Title of article
Glioma Models: New GEMMs Add “Class” with Genomic and Expression Correlations
Author/Authors
Maire، نويسنده , , Cécile L. and Ligon، نويسنده , , Keith L.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
3
From page
295
To page
297
Abstract
Malignant gliomas are characterized by accumulated aberrations affecting TP53, PTEN, and RB1 signaling. In this issue, Chow et al. discover that combinatorial loss of these tumor suppressors in mice induces gliomas with unexpected degrees of similarity to human pathologic, genomic, and expression subclasses recently revealed by large-scale genomic studies.
Journal title
Cancer Cell
Serial Year
2011
Journal title
Cancer Cell
Record number
1337432
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