• Title of article

    Breaking the LSD1/KDM1A Addiction: Therapeutic Targeting of the Epigenetic Modifier in AML

  • Author/Authors

    Lokken، نويسنده , , Alyson A. and Zeleznik-Le، نويسنده , , Nancy J.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2012
  • Pages
    3
  • From page
    451
  • To page
    453
  • Abstract
    KDM1A/LSD1, a histone H3K4/K9 demethylase and epigenetic regulator with roles in both gene activation and repression, has increased expression in multiple cancer types. Harris et al., in this issue of Cancer Cell, and Schenk et al. show that KDM1A may be a viable therapeutic target in treating AML.
  • Journal title
    Cancer Cell
  • Serial Year
    2012
  • Journal title
    Cancer Cell
  • Record number

    1337849