Author/Authors :
Safaei، Akbar نويسنده Department of Pathology, Shahid Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran , , Tabib، Seyed Masood نويسنده Internal ward, Boushehr University of Medical Sciences, Boushehr , , Farzaneh، Mohamad Reza نويسنده Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran , , Shahryari، Jahanbanoo نويسنده Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran , , Bahmaniar، Mohamad نويسنده Dept. of Pathology, Fatemeh Zahra Hospital, Boushehr University of Medical Sciences, Boushehr ,
Abstract :
Although gastrointestinal involvement by metastatic malignant melanoma is common but
primary gastrointestinal (GI) melanoma has been reported in rare cases. In this study we report
two cases of primary gastrointestinal malignant melanoma that one of them is a known case of
neurofibromatosis type 1(NF1). Both cases showed no evidence of any lesions in skin and eye.
Malignant melanoma of GI tract in patient with neurofibroma is reported with hypothesis of a
possible relation between two pathologies. Both primary GI melanoma and combination of NF1
with primary GI melanoma are rare entities discussed in this article.