Author/Authors :
Beladi Mousavi، Seyed Seifollah نويسنده Assistant Professor, Department of Nephrology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran , , Hajiani، Eskandar نويسنده , , Hayati، Fatemeh نويسنده Section of Nephrology, Department of Internal Medicine, Emam Hospital, Ahwaz Jundishapur Uni-versity of Medical Sciences, Ahwaz, Iran , , Hashemi ، Seyed Jalal نويسنده 1. Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvvaz, Iran , , Shayesteh، Aliakbar نويسنده Division of Gastroenterology, Department of Internal Medicine, Emam Hospital, Ahwaz Jundishapur University of Medical Sciences, Ahwaz, Iran , , Salehi Behbehani، Seyed Mohammad نويسنده Section of Nephrology, Department of Internal Medicine, Emam Hospital, Ahwaz Jundishapur Uni-versity of Medical Sciences, Ahwaz, Iran , , Masjedi Zadeh، Abdorrahim نويسنده Division of Gastroenterology, Department of Internal Medicine, Emam Hospital, Ahwaz Jundishapur University of Medical Sciences, Ahwaz, Iran , , Beladi Mousavi ، M نويسنده Section of Nephrology, Department of Internal Medicine, Emam Hospital, Ahwaz Jundishapur Uni-versity of Medical Sciences, Ahwaz, Iran ,
Abstract :
Objective: Liver disease caused by hepatitis C virus (HCV) in patients with end-stage renal disease (ESRD) causes significant morbidity and mortality. The aim of this study was to determine the prevalence of HCV infection and its relationship in ESRD patients living in the province of Khuzestan, Iran.
Material and Methods: In a cross sectional study from December 2010 to March 2011, entire of ESRD patients treated with hemodialysis (HD) or peritoneal dialysis (PD) in the Khuzestan province enrolled for the study. A standardized questionnaire was used to collect Social and demographic data including cause of ESRD and date of onset of PD or HD. Blood samples were tested for hepatitis C antibody (anti-HCV) by enzyme-linked immunosorbent assays (ELISA). The Research Center of Ahvaz Joundishapur University of Medical Sciences approved the study.
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Results: In overall, 1117 ESRD patients were enrolled for the study. The prevalence of
anti-HCV was 3.4 % (38 patients, 20 males with Mean age of 45.29 years and 18 females
with Mean age of 45.6 years). The most common Cause of ESRD in anti-HCV
positive patients was high blood pressure in 45.4%, followed by, DM in 28.7%, and
unknown in 13.9%. We din not find any association between both sexes (P = 0.06) and
also between mean age of anti-HCV positive and negative patients (P = 0.59). There was
a significant association between high blood pressure as cause of ESRD with anti-HCV
positivity (0.033).
Conclusion: Although, the prevalence of HCV infection among ESRD patients has
decreased in recent years, however it remains as a significant cause of viral hepatitis
among these patients in Khuzestan province.
