Author/Authors :
Izadi، Sadegh نويسنده Department of Neurology, Motahari Clinic, Shiraz University of Medical Sciences, Shiraz, Iran; , , Karamimagham، Sina نويسنده MD, Fellowship of Neonatology, Department of Pediatric, Medical School , , Poursadeghfard، Maryam نويسنده MD, Assistant Professor of Neurology, Department of Neurology, Medical School ,
Abstract :
Chronic Inflammatory Demyelinating Polyneuropathy is an autoimmune disease with progressive and relapsing courses. The main clinical presentations are diffuse deep tendon hyporeflexia or areflexia and symmetric prox-imal-distal muscles weakness. Myasthenia gravis is also an immune mediated disease with fluctuating ocular and bulbar symptoms and sometimes weakness. Although both myasthenia gravis and chronic inflammatory demyelinating polyneuropathy are immune mediated disorders, clinical presentations are obviously different in the two diseases.
Herein, we will report a case of chronic inflammatory demyelinating polyneuropathy who presented with isolat-ed unilateral ptosis. Initially, the patient was managed as ocular type of myasthenia gravis, but after progres-sion to general limb weakness and areflexia, the diagnosis of chronic inflammatory demyelinating polyneurop-athy was made. Although unilateral ptosis is a typical feature of myasthenia gravis, it may be seen as the first presentation of chronic inflammatory demyelinating polyneuropathy as well which mimics myasthenia gravis disease.