Palladium-catalyzed asymmetric allylic alkylation using chiral hydrazone ligands with ferrocene skeleton

Palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate (4) with a dimethyl malonate–BSA–LiOAc system has been successfully carried out in the presence of chiral phosphine–hydrazone ligands such as 3a in good yields with good enantioselectivities (up to 84% ee).