β-Carbonylsilanes with a silacyclohexane skeleton and additional C-functionalized organyl groups at the silicon atom: synthesis, reactivity, and NMR-spectroscopic characterization

A series of novel β-carbonylsilanes, with a silacyclohexane skeleton and additional C-functionalized organyl groups at the silicon atom, were synthesized, their reactivity was explored, and they were structurally characterized by multinuclear NMR spectroscopy. The aim of these investigations was to provide the basis for the development of novel silicon-based drugs containing a silacyclohexane skeleton, with a CH2C(O)R substituent and an additional C-functionalized organyl group at the silicon atom.