Title of article
New metallocene-bridged cyclodextrin dimer: A stable derivative of the antitumor drug titanocene dichloride and its potent cytotoxity against human breast cancer (MCF-7) cells
Author/Authors
Zhenda Lu، نويسنده , , Changsheng Lu، نويسنده , , Xiaoming Ren، نويسنده , , Qingjin Meng، نويسنده ,
Issue Information
دوفصلنامه با شماره پیاپی سال 2006
Pages
5
From page
5895
To page
5899
Abstract
A novel cyclodextrin dimer bridged with titanocene moiety, titanocene di[mono[6-deoxy-6-(2-(thio-1,2-dicyane ethylenylthio)ethyl thio-1,2-dicyane ethylenylthio)]-β-cyclodextrin] (6), has been synthesized and characterized by IR spectroscopy, UV spectroscopy, thermogravimetry, MALDI-TOF MS spectrum, 1H and 13C NMR spectroscopy. Especially, its potent cytotoxity against Human Breast Cancer (MCF-7) has also been studied.
Keywords
2-dicyane ethylenylthio)ethyl thio-1 , 2-dicyane ethylenylthio)]-?-cyclodextrin] , Titanocene complex , ?-Cyclodextrin dimer , Cytotoxity
Journal title
Journal of Organometallic Chemistry
Serial Year
2006
Journal title
Journal of Organometallic Chemistry
Record number
1379723
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