• Title of article

    Solid-Phase Synthesis of Peptide-Derived Enantiospecific Nucleic Acid Analogs

  • Author/Authors

    Shah، نويسنده , , Vibhakar J. and Cerpa، نويسنده , , Robert R. Kuntz، نويسنده , , Jr.، نويسنده , , Irwin D. and Kenyon، نويسنده , , George L.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    201
  • To page
    206
  • Abstract
    The first solid-phase synthesis of novel peptide-derived enantiospecific nucleic acid analogs (PDNAs), employing all three stereoisomers of 4-(N9-adeninyl)-2-amino(t-boc)-butyric acid as ADNA (amino acid-derived nucleoside analogs) monomers has been described. The preliminary melting temperature (Tm) data obtained by hybridization experiments demonstrated that these PDNAs can anneal to their complementary nucleic acid strand dT10.
  • Journal title
    Bioorganic Chemistry: an International Journal
  • Serial Year
    1996
  • Journal title
    Bioorganic Chemistry: an International Journal
  • Record number

    1385189