Title of article :
A study of the effect on nucleophilic hydrolytic activity of pancreatic elastase, trypsin, chymotrypsin, and leucine aminopeptidase by boronic acids in the presence of arabinogalactan: a subsequent study on the hydrolytic activity of chymotrypsin by boron
Author/Authors :
Smoum، نويسنده , , Reem and Rubinstein، نويسنده , , Abraham and Srebnik، نويسنده , , Morris، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
The hydrolytic activity of trypsin, chymotrypsin, elastase, and leucine aminopeptidase, is inhibited by different boronic acids. However, all the enzymes are inhibited by the compound CbzAla(boro)Gly(OH)2. Therefore, these additives can control the nucleophilic hydrolytic activity of these enzymes.
Keywords :
Saccharides , Hydrolytic activity , Inhibition , Boronic acids , Serine proteases
Journal title :
Bioorganic Chemistry: an International Journal
Journal title :
Bioorganic Chemistry: an International Journal