Title of article :
An improved route to the synthetic of diphenyl α-(diethoxythiophosphorylamino)methylphosphonates
Author/Authors :
Miao، نويسنده , , Zhiwei and Wang، نويسنده , , Bin and Zhang، نويسنده , , Gaihong and Chen، نويسنده , , Ruyu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
An improved method for the synthesis of Diphenyl α-(diethoxythiophosphorylamino)methylphosphonates under mild conditions is described. It consists of the reaction of diethyl thiophosphoramidate (1) with triphenyl phosphite (3) and a substituted benzylaldehyde or ketone (2) by a one-pot procedure with the aid of acetyl chloride.
Keywords :
Mannich type reaction , X-ray crystal structure , Thiophosphate-phosphonate derivatives , acetyl chloride
Journal title :
Bioorganic Chemistry: an International Journal
Journal title :
Bioorganic Chemistry: an International Journal