Title of article :
Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents
Author/Authors :
Varaprasad، نويسنده , , Chamakura V.N.S. and Ramasamy، نويسنده , , Kanda S. and Girardet، نويسنده , , Jean-Luc and Gunic، نويسنده , , Esmir and Lai، نويسنده , , Vicky and Zhong، نويسنده , , Weidong and An، نويسنده , , Haoyun and Hong، نويسنده , , Zhi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Pages :
10
From page :
25
To page :
34
Abstract :
Several Toyocamycin (4) analogues were examined for their ability to inhibit HCV RNA in a replicon assay. Among the compounds examined 4-methylthio (18) and 5-carboxamide oxime derivatives (23 and 27) of Toyocamycin were found to have good activity and selectivity.
Keywords :
HCV NS5B inhibitors , Toyocamycin , 3-d]pyrimidine nucleosides
Journal title :
Bioorganic Chemistry: an International Journal
Serial Year :
2007
Journal title :
Bioorganic Chemistry: an International Journal
Record number :
1385891
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1385891
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