Title of article :
The effects of automated plasmapheresis on clinical, haematological, biochemical and coagulation variables in horses
Author/Authors :
Feige، نويسنده , , K. and Ehrat، نويسنده , , F.B. and Kنstner، نويسنده , , S.B.R. and Wampfler، نويسنده , , B.، نويسنده ,
Issue Information :
فصلنامه با شماره پیاپی سال 2005
Pages :
6
From page :
102
To page :
107
Abstract :
The goal of this study was to determine the effects of plasmapheresis on the behaviour, general condition, haematological, biochemical and coagulation variables of donor horses for 32 days following the procedure. Twenty millilitres of plasma/kg body weight were collected via plasmapheresis in six clinically healthy horses. neral behaviour and condition of the horses was not affected by the procedure. During plasmapheresis, there was a mild increase in the haematocrit, haemoglobin concentration and total erythrocyte and leucocyte counts (P<0.01). The mean concentrations of total protein and albumin decreased significantly (P<0.01) and total protein did not normalise for about three weeks. Several other biochemical variables also decreased significantly during plasmapheresis, but mostly remained within reference ranges. After plasmapheresis, the mean value of the activated partial thromboplastin time and the thrombin time were mildly but significantly increased (P<0.01), and the mean activities of factor V, factor VIII and antithrombin decreased significantly (P<0.01), although all coagulation values remained within reference ranges. sults indicate that, in horses, the collection of 20 mL of plasma/kg body weight via plasmapheresis results in mild changes in several haematological, biochemical and coagulation variables, although these were of no clinical relevance for the donors.
Keywords :
PLASMA , coagulopathies , Horse , Coagulation variables , Plasmapheresis
Journal title :
The Veterinary Journal
Serial Year :
2005
Journal title :
The Veterinary Journal
Record number :
1390764
Link To Document :
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