Author/Authors :
J. Barrs، نويسنده , , V.R. and Halliday، نويسنده , , C. and Martin، نويسنده , , P. and Wilson، نويسنده , , B. and Krockenberger، نويسنده , , M. and Gunew، نويسنده , , M. and Bennett، نويسنده , , S. and Koehlmeyer، نويسنده , , E. and Thompson، نويسنده , , A. and Fliegner، نويسنده , , R. and Hocking، نويسنده , , A. and Sleiman، نويسنده , , S. and O’Brien، نويسنده , , C. and Beatty، نويسنده , , J.A.، نويسنده ,
Abstract :
Aetiology, clinicopathological findings and treatment outcomes were documented in 23 cats (1.5–13 years of age) with sinonasal (SNA, n = 6) or sino-orbital (SOA, n = 17) aspergillosis. Cases recruited retrospectively and prospectively were included if fungal hyphae were identified on cytological or histological examination and the fungal pathogen was identified by PCR and DNA sequencing (ITS1 or ITS1-5.8S-ITS2 regions, rDNA gene cluster).
culture was positive in 22/23 cases. In cases of SNA, the fungal pathogen was Aspergillus fumigatus (n = 4), Neosartorya fischeri or A. lentulus (n = 1) or a non-speciated Neosartorya spp. (n = 1). In all cases of SOA (n = 17), the fungal pathogen was identified as Neosartorya spp. Nine cats had brachycephalic conformation. Cats with SNA were more likely to be infected with A. fumigatus and had a better prognosis than cats with SOA.
Keywords :
Sinonasal , Cats , Neosartorya spp. , aspergillosis , Sino-orbital , Aspergillus spp.
