Electrochemical impedance measurements for the investigation of odorants interaction with thiol layer immobilized onto gold electrode

The impedance measurements were used for the detection of the interaction of smell compounds with thiol layer deposited onto gold electrode. The following compounds were selected for the study: geraniol, coumarin, menthol, 1-octanol, β-ionone. The changes of the resistance and capacitance of the thiol layer, occurred under stimulation by odorants, calculated on the base of impedance measurements, were correlated with other parameters describing physico-chemical properties (partition coefficients log P) and topological one such as total surface area (TSA) and van der Waals’ volume (VDW).