Title of article
Solubility of coenzyme Q10 in supercritical carbon dioxide
Author/Authors
Matias، نويسنده , , Ana A. and Nunes، نويسنده , , Ana V.M. and Casimiro، نويسنده , , Teresa and Duarte، نويسنده , , Catarina M.M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
6
From page
201
To page
206
Abstract
The equilibrium solubility of coenzyme Q10 (CoQ10) in supercritical carbon dioxide (scCO2) was measured by a static analytical method in the pressure range from 9 to 26 MPa, at temperatures of 305, 313 and 323 K. The cosolvent effect of ethanol in the solubility of the bioactive compound in scCO2 has been investigated, at 15 MPa and 313 K. A preliminary study of the viability of extracting CoQ10 with scCO2 has been investigated at 15 MPa and 313 K, using the content of commercial pharmaceutical capsules as the solid matrix feed. The solubility data results were correlated by use of the empirical density-based Chrastil model.
Keywords
coenzyme Q10 , Supercritical fluid extraction , Ubiquinone 50 , Density-based correlation , Equilibrium solubility
Journal title
Journal of Supercritical Fluids
Serial Year
2004
Journal title
Journal of Supercritical Fluids
Record number
1424574
Link To Document