Author/Authors :
Ambrosi، نويسنده , , D. and Ateshian، نويسنده , , G.A. and Arruda، نويسنده , , E.M. and Cowin، نويسنده , , S.C. and Dumais، نويسنده , , J. and Goriely، نويسنده , , A. and Holzapfel، نويسنده , , G.A. and Humphrey، نويسنده , , J.D. and Kemkemer، نويسنده , , R. and Kuhl، نويسنده , , E. and Olberding، نويسنده , , J.E. and Taber، نويسنده , , L.A. and Garikipati، نويسنده , , K.، نويسنده ,
Abstract :
The continuum mechanical treatment of biological growth and remodeling has attracted considerable attention over the past fifteen years. Many aspects of these problems are now well-understood, yet there remain areas in need of significant development from the standpoint of experiments, theory, and computation. In this perspective paper we review the state of the field and highlight open questions, challenges, and avenues for further development.
Keywords :
Morphogenesis , computational mechanics , Thermodynamics , mechanotransduction , Chemo-mechanics
