Title of article :
The bipolar disorder prodrome revisited: Is there a symptomatic pattern?
Author/Authors :
Zeschel، نويسنده , , Eike and Correll، نويسنده , , Christoph U. and Haussleiter، نويسنده , , Ida S. and Krüger-ضzgürdal، نويسنده , , Seza and Leopold، نويسنده , , Karolina and Pfennig، نويسنده , , Andrea and Bechdolf، نويسنده , , Andreas and Bauer، نويسنده , , Michael and Juckel، نويسنده , , Georg، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Pages :
10
From page :
551
To page :
560
Abstract :
AbstractObjectives ess the phenomenology and course of pre-(hypo)manic and pre-depressed prodromal symptoms, including mood swings, as precursors of bipolar disorder (BD) in a German multi-center study. s tructured interviews [Bipolar Prodrome Symptom Scale-Retrospective (BPSS-R); Semi-structured Interview for Mood Swings] were administered to patients within 8 years of BD (BD I, BD II) onset. s two outpatients were included (40.5% male, mean age 35.1±10.0 years, illness onset at 30.5±9.5 years). Feeling extremely energetic (85.7%), racing thoughts (78.6%), physical agitation (76.2%), overtalkativeness (71.4%), and low sleep requirement (71.4%) occurred most frequently prior to the first (hypo)manic episode, whereas depressed mood (83.0%), reduced vitality (81.0%), physical exhaustion (78.6%), tiredness (76.2%), and insomnia (66.7%) preceded pre-depressively. Mood lability (p=.006), odd ideas (p=.003) and the psychosis index score (p=.003) differed significantly in prevalence depending on the episodes’ mood. Extremely energetic (p=.046), overtalkativeness (p<.001), and racing thoughts (p=.013) lasted significantly longer prior to depression. Neither severity nor frequency of prodromal symptoms differed significantly. Most of the symptoms emerged during the proximal prodromal phase. Links between mood swings and subsequent BD were found. tions ms were evaluated retrospectively with self-reporting tools in bipolar patients from academic treatment settings without comparison to clinical controls. sions ly specific depressive or manic but also general symptoms occurred prior to both affective episodes. The pre-depressive prodrome lasted longer than the pre-manic one, but severity and frequency did not differ significantly. Mood swings and disturbed diurnal rhythm occurred prior to both episodes as early signs of BD.
Keywords :
Prodrome , bipolar disorder , MANIA , Early recognition , mood swings
Journal title :
Journal of Affective Disorders
Serial Year :
2013
Journal title :
Journal of Affective Disorders
Record number :
1434202
Link To Document :
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