Title of article
Base pair mismatch identification with DNA nanoswitch and long lifetime acridine fluorophore
Author/Authors
McGuinness، نويسنده , , Colin D. and Keszenman-Pereyra، نويسنده , , David and Dickinson، نويسنده , , Paul S. Campbell، نويسنده , , Colin J. and Maltman، نويسنده , , Beatrice A. and Bachmann، نويسنده , , Till T. and Ghazal، نويسنده , , Peter and Crain، نويسنده , , Jason، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
5
From page
342
To page
346
Abstract
Detection of single base pair mutations in an unlabelled nucleic acid target sequence is demonstrated using the time-resolved measurement of the Fِrster Resonance Energy Transfer (FRET) between a long lifetime acridine-based fluorophore and a non-fluorescent quencher molecule covalently bound to a DNA Holliday junction-based nanoswitch.
Keywords
FRET , Single photon counting , DNA , holliday junction , fluorescence
Journal title
Sensors and Actuators B: Chemical
Serial Year
2010
Journal title
Sensors and Actuators B: Chemical
Record number
1438660
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