Physiochemical microparticle sensors based on nonlinear magnetic oscillations

Recently, the nonlinear rotation of single magnetic particles has emerged as a tool to measure physical parameters on the micro-scale. In this paper, detailed theoretical analyses are carried out for tailored microprobes that measure (1) local magnetic fields, (2) magnetic particle characteristics, (3) viscosity and (4) chemical binding, along with their corresponding experimental demonstrations. Such new physical measurement methods, using single micro- or nano-particles, in combination with previous chemical nanoparticle sensing methods, lead to a new class of physiochemical micro- and nano-particle sensors that may be of significant biomedical and technological interest.