Fiber-optic biosensor based on lossy mode resonances

In this work, a novel fiber-optic immunoglobulin G biosensor based on lossy mode resonances is proposed. This physical phenomenon is obtained by depositing a PAH/PSS layer-by-layer thin-film on a cladding removed optical fiber. A reflective configuration is used to track the generation and response of the electromagnetic resonance in the different phases of the process. According to the results, wavelength displacements of 10 nm are visualized when detecting immunoglobulins with a response time of 12 min for a 50 μg/ml concentration.