• Title of article

    A BODIPY fluorescent probe with selective response for hypochlorous acid and its application in cell imaging

  • Author/Authors

    Gai، نويسنده , , Lizhi and Mack، نويسنده , , John and Liu، نويسنده , , Hui and Xu، نويسنده , , Zheng and Lu، نويسنده , , Hua and Li، نويسنده , , Zhifang، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2013
  • Pages
    6
  • From page
    1
  • To page
    6
  • Abstract
    A boron-dipyrromethene (BODIPY) derivative with a hydroxymethyl group at the meso-position, 1, was synthesized, which exhibits a highly specific and rapid ‘turn-off’ response for HOCl during confocal fluorescence microscopy experiments under physiological conditions and in live cells. The formation of an electron-withdrawing formyl substituent upon oxidation results in highly efficient nonradiative decay of the S1 state and hence in a drastic decrease in fluorescence emission intensity.
  • Keywords
    Hypochlorous acid , TD-DFT , Fluorescent probe , Cell image , BODIPY
  • Journal title
    Sensors and Actuators B: Chemical
  • Serial Year
    2013
  • Journal title
    Sensors and Actuators B: Chemical
  • Record number

    1441917