Comparison between ECIS and LAPS for establishing a cardiomyocyte-based biosensor

Electrical cell–substrate impedance sensor (ECIS) and light-addressable potentiometric sensor (LAPS) are becoming powerful tools for monitoring the cell growth status and cell metabolism. This work describes the ECIS- and LAPS-type cardiomyocyte-based biosensors. The working principle and detection systems of transducers were presented. In particular, our investigation is devoted to some basic characteristic tests of these transducers for the purpose of comparing their performance related to cardiomyocyte-based biosensors evaluation. Finally, cardiomyocyte-based biosensors performance was displayed and analyzed. From the results, both of transducers are promising tools to establishing the cardiomyocyte-based biosensors.