Aggregation of bioinformatics data using Semantic Web technology

The integration of disparate biomedical data continues to be a challenge for drug discovery efforts. Semantic Web technologies provide the capability to more easily aggregate data and thus can be utilized to improve the efficiency of drug discovery. We describe an implementation of a Semantic Web infrastructure that utilizes the scalable Oracle Resource Description Framework (RDF) Data Model as the repository and Seamark Navigator for browsing and searching the data. The paper presents a use case that identifies gene biomarkers of interest and uses the Semantic Web infrastructure to annotate the data.