Title of article
AC-magnetic field controlled drug release from magnetoliposomes: design of a method for site-specific chemotherapy
Author/Authors
Babincov?، نويسنده , , M and ?i?manec، نويسنده , , P and Altanerov?، نويسنده , , V and Altaner، نويسنده , , ? and Babinec، نويسنده , , P، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
17
To page
19
Abstract
Large unilamellar magnetoliposomes (MLs) with encapsulated doxorubicin (DOX) (anticancer drug) were prepared by reverse-phase evaporation. They were exposed to an alternating magnetic field with a frequency of 3.5 MHz and an induction of 1.5 mT produced in three-turn pancake coil. The results showed that magnetoliposomes could be specifically heated to 42 °C (phase transition temperature of a used lipid) in a few minutes and during this, the encapsulated doxorubicin is massively released.
Keywords
Alternating magnetic field , Magnetoliposomes , Drug release , doxorubicin , hyperthermia , Cancer Therapy
Journal title
Bioelectrochemistry
Serial Year
2002
Journal title
Bioelectrochemistry
Record number
1450269
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