Title of article
Electrochemical DNA biosensor for analysis of wastewater samples
Author/Authors
Lucarelli، نويسنده , , F and Kicela، نويسنده , , A and Palchetti، نويسنده , , I and Marrazza، نويسنده , , G and Mascini، نويسنده , , M، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
6
From page
113
To page
118
Abstract
The application of a disposable electrochemical DNA biosensor to wastewater samples is reported. The DNA biosensor is assembled by immobilising double-stranded calf thymus DNA on the surface of a disposable, carbon screen-printed electrode (SPE). The oxidation signal of the guanine base, obtained by a square wave voltammetric scan, is used as analytical signal. The presence of compounds with affinity for DNA is measured by their effect on the guanine oxidation. The comparison of the results with a toxicity test based on bioluminescent bacteria has confirmed the applicability of the method to real samples.
Keywords
Wastewater samples , Toxalert® 100 , DNA biosensor , Screen-printed electrodes
Journal title
Bioelectrochemistry
Serial Year
2002
Journal title
Bioelectrochemistry
Record number
1450563
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