Title of article
The effect of polyamidoamine dendrimers on human erythrocyte membrane acetylcholinesterase activity
Author/Authors
Klajnert، نويسنده , , B. and Sadowska، نويسنده , , M. and Bryszewska، نويسنده , , M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
23
To page
26
Abstract
Polyamidoamine (PAMAM) dendrimers impact on activity of acetylcholinesterase was studied. It has been shown that dendrimers induce a biphasic effect: depending on their concentrations they increase or decrease enzyme activity. It may be due to two types of interactions: direct—between dendrimers and the enzyme; indirect—via a modification of the physical state of membrane phospholipids affecting the acetylcholinesterase.
Keywords
Acetylcholinesterase , Michaelis–Menten constant , Erythrocyte membrane , dendrimer , Erythrocyte ghosts
Journal title
Bioelectrochemistry
Serial Year
2004
Journal title
Bioelectrochemistry
Record number
1451263
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