Author/Authors :
Ozsoz، نويسنده , , Mehmet and Erdem، نويسنده , , Arzum and ضzkan، نويسنده , , Dilsat and Kara، نويسنده , , Pinar and Karadeniz، نويسنده , , Hakan and Meric، نويسنده , , Burcu and Kerman، نويسنده , , Kagan and Girousi، نويسنده , , Stella، نويسنده ,
Abstract :
Electrochemical DNA biosensors have become strong candidates for DNA based analysis. Allele-specific genotyping is also one of the important research areas, where electrochemical approaches provide promising advances. Recently reported two methods based on electrochemical guanine and colloidal gold (Au) nanoparticle oxidation signals are reviewed and compared with the existing genotyping methods in this report.
Keywords :
Electrochemical DNA biosensor , Factor V Leiden mutation , Polymerase chain reaction (PCR) , Allele-specific genotyping , Mutation