• Title of article

    A neural network for predicting the stability of RNA/DNA hybrid duplexes

  • Author/Authors

    Ma، نويسنده , , Lixin and Cheng، نويسنده , , Changmei and Liu، نويسنده , , Xiaohong and Zhao، نويسنده , , Yufen and Wang، نويسنده , , Anlin and Herdewijn، نويسنده , , Piet، نويسنده ,

  • Issue Information
    دوفصلنامه با شماره پیاپی سال 2004
  • Pages
    6
  • From page
    123
  • To page
    128
  • Abstract
    A back propagation (BP) neural network (NN) method has been developed to predict the stability of RNA/DNA duplex. Calculated Tm of hybrid formation with the present parameters fits the experimental values within reasonable errors (AD=1.2887 K, SEP=1.782, R2=0.9673 for NN1; AD=2.1388 K, SEP=3.506, R2=0.8889 for NN2). And it has the advantage that the determinations of thermodynamic parameters (TP) are not needed.
  • Journal title
    Chemometrics and Intelligent Laboratory Systems
  • Serial Year
    2004
  • Journal title
    Chemometrics and Intelligent Laboratory Systems
  • Record number

    1460872