• Title of article

    Solving chemical master equations by adaptive wavelet compression

  • Author/Authors

    Jahnke، نويسنده , , Tobias and Udrescu، نويسنده , , Tudor، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    18
  • From page
    5724
  • To page
    5741
  • Abstract
    Solving chemical master equations numerically on a large state space is known to be a difficult problem because the huge number of unknowns is far beyond the capacity of traditional methods. We present an adaptive method which compresses the problem very efficiently by representing the solution in a sparse wavelet basis that is updated in each step. The step-size is chosen adaptively according to estimates of the temporal and spatial approximation errors. Numerical examples demonstrate the reliability of the error estimation and show that the method can solve large problems with bimodal solution profiles.
  • Keywords
    Wavelet compression , Adaptive step-size selection , Adaptive Galerkin approximation , gene regulatory networks , Stochastic reaction kinetics , Chemical master equation , Rothe’s method
  • Journal title
    Journal of Computational Physics
  • Serial Year
    2010
  • Journal title
    Journal of Computational Physics
  • Record number

    1482485