Pathogens on meat and infection in animals – Establishing a relationship using campylobacter and salmonella as examples

A high proportion of human campylobacter and salmonella infections is likely to originate from farm animals, usually directly from the consumption of contaminated meat or milk. Surveillance shows that campylobacter and salmonella genotypes are shared between human case isolates, farm animals and foods, although with the latter there can be marked differences between infection frequency in live animals and contamination rates in raw foods. This is supported by a variety of data from around the world, using a range of different methods. In this paper the evidence for farm animals being the reservoir of human salmonella and campylobacter infection is presented. However, a note of caution is sounded about the complex nature of zoonotic diseases caused by these two pathogens. Thus, many salmonellas and campylobacter types found routinely in food animals do not appear to cause human infections. Is this and artefact of the surveillance and/or microbiological methods used or are some strains of these bacteria genuinely non-pathogenic in man?