Novel use of a dual-zone restricted access sorbent: normal-phase solid-phase extraction separation of methyl oleate from polynuclear aromatic hydrocarbons stemming from semi-permeable membrane devices

A normal-phase solid-phase extraction (SPE) method was developed utilizing a dual-zone restricted-access sorbent to separate methyl oleate from the 16 US Environmental Protection Agency priority-pollutant polynuclear aromatic hydrocarbons in a hexane matrix. This technique represents a new development in SPE methodology expanding the limited number of available normal-phase SPE sorbents. While based on a specific application (removal of methyl oleate from semipermeable membrane device extracts), this cleanup method could easily be adapted for other uses requiring the removal/isolation of methyl oleate and potentially related compounds.