3D-1D simulation of flow in Fontan operation: Effects of antegrade flow on flow pulsations

This study considers blood ow in total cavopulmonary connection (TCPC) morphology created in Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood ow pulsatility since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary ow pulsations by keeping Main Pulmonary Artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the eects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary ow pulsations. The 3D geometry is reconstructed from CT angiography scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. We applied a 3D-1D coupled method to simulate blood ow in this situation more precisely. The results show that adding AF increases Pulsatility Index (PI) in both Left and Right Pulmonary Artery (LPA and RPA respectively). Moreover, adding AF leads to an increase in energy loss. It also increases the pulmonary-to-systemic ow ratio leading to increase in total cardiac ow rate and hence heart power